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SMILES: Cc1cnc2sc(CC(=O)Nc3sccc3C(N)=O)cn12

InChI Key: InChIKey=WAJFVMITTUEWIA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50342311   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Mitogen-activated protein kinase 8


(Homo sapiens (Human))		BDBM50342311
PNG
(2-(2-(5-methylimidazo[2,1-b]thiazol-2-yl)acetamido...)
Show SMILES Cc1cnc2sc(CC(=O)Nc3sccc3C(N)=O)cn12
Show InChI InChI=1S/C13H12N4O2S2/c1-7-5-15-13-17(7)6-8(21-13)4-10(18)16-12-9(11(14)19)2-3-20-12/h2-3,5-6H,4H2,1H3,(H2,14,19)(H,16,18)
PDB
MMDB

NCI pathway
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KEGG

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Article
PubMed
n/an/a 2.50E+3n/an/an/an/an/an/a



Sanford-Burnham Medical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of JNK1 by TR-FRET assay

Bioorg Med Chem 19: 2582-8 (2011)


Article DOI: 10.1016/j.bmc.2011.03.017
BindingDB Entry DOI: 10.7270/Q2J966PD
More data for this
Ligand-Target Pair