BDBM50342315 2-(2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acetamido)thiophene-3-carboxamide::CHEMBL1767247

SMILES: NC(=O)c1ccsc1NC(=O)Cc1ccc2OCCOc2c1

InChI Key: InChIKey=NVIOJYZRUWJFJF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50342315   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM50342315 (2-(2-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)acetamid...) Show SMILES NC(=O)c1ccsc1NC(=O)Cc1ccc2OCCOc2c1 Show InChI InChI=1S/C15H14N2O4S/c16-14(19)10-3-6-22-15(10)17-13(18)8-9-1-2-11-12(7-9)21-5-4-20-11/h1-3,6-7H,4-5,8H2,(H2,16,19)(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sanford-Burnham Medical Research Institute Curated by ChEMBL					Assay Description Inhibition of JNK1 by TR-FRET assay				Bioorg Med Chem 19: 2582-8 (2011) Article DOI: 10.1016/j.bmc.2011.03.017 BindingDB Entry DOI: 10.7270/Q2J966PD
					More data for this Ligand-Target Pair