BDBM50342330 2-(2-(4-(trifluoromethoxy)phenyl)acetamido)thiophene-3-carboxamide::CHEMBL1767274

SMILES: NC(=O)c1ccsc1NC(=O)Cc1ccc(OC(F)(F)F)cc1

InChI Key: InChIKey=PDFZLTDPKVADIY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50342330   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM50342330 (2-(2-(4-(trifluoromethoxy)phenyl)acetamido)thiophe...) Show SMILES NC(=O)c1ccsc1NC(=O)Cc1ccc(OC(F)(F)F)cc1 Show InChI InChI=1S/C14H11F3N2O3S/c15-14(16,17)22-9-3-1-8(2-4-9)7-11(20)19-13-10(12(18)21)5-6-23-13/h1-6H,7H2,(H2,18,21)(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sanford-Burnham Medical Research Institute Curated by ChEMBL					Assay Description Inhibition of JNK1 by TR-FRET assay				Bioorg Med Chem 19: 2582-8 (2011) Article DOI: 10.1016/j.bmc.2011.03.017 BindingDB Entry DOI: 10.7270/Q2J966PD
					More data for this Ligand-Target Pair