BDBM50342337 2-(2-(4-(furan-2-ylmethyl)piperazin-1-yl)acetamido)thiophene-3-carboxamide::CHEMBL1767293

SMILES: NC(=O)c1ccsc1NC(=O)CN1CCN(Cc2ccco2)CC1

InChI Key: InChIKey=WGSJNPLNIZFTPS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50342337   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM50342337 (2-(2-(4-(furan-2-ylmethyl)piperazin-1-yl)acetamido...) Show SMILES NC(=O)c1ccsc1NC(=O)CN1CCN(Cc2ccco2)CC1 Show InChI InChI=1S/C16H20N4O3S/c17-15(22)13-3-9-24-16(13)18-14(21)11-20-6-4-19(5-7-20)10-12-2-1-8-23-12/h1-3,8-9H,4-7,10-11H2,(H2,17,22)(H,18,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Sanford-Burnham Medical Research Institute Curated by ChEMBL					Assay Description Inhibition of JNK1 by TR-FRET assay				Bioorg Med Chem 19: 2582-8 (2011) Article DOI: 10.1016/j.bmc.2011.03.017 BindingDB Entry DOI: 10.7270/Q2J966PD
					More data for this Ligand-Target Pair