BDBM50342388 3-Amino-6-(2-dimethylamino-ethylamino)-4-methylthieno[2,3-b]pyridine-2-carboxylic acid(1-methyl-1H-pyrrol-2-yl-methylene)-hydrazide::CHEMBL1765556

SMILES: CN(C)CCNc1cc(C)c2c(N)c(sc2n1)C(=O)N\N=C\c1cccn1C

InChI Key: InChIKey=MDDWNKJYXSHXOI-SSDVNMTOSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50342388   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50342388 (3-Amino-6-(2-dimethylamino-ethylamino)-4-methylthi...) Show SMILES CN(C)CCNc1cc(C)c2c(N)c(sc2n1)C(=O)N\N=C\c1cccn1C Show InChI InChI=1S/C19H25N7OS/c1-12-10-14(21-7-9-25(2)3)23-19-15(12)16(20)17(28-19)18(27)24-22-11-13-6-5-8-26(13)4/h5-6,8,10-11H,7,9,20H2,1-4H3,(H,21,23)(H,24,27)/b22-11+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	246	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibition of c-SRC assessed as residual activity using KVEKIGEGYYGVVYK as peptide substrate after 20 mins by scintillation counting				Bioorg Med Chem 19: 2517-28 (2011) Article DOI: 10.1016/j.bmc.2011.03.021 BindingDB Entry DOI: 10.7270/Q2DN45CD
					More data for this Ligand-Target Pair