BDBM50342542 2-phenethyl-6,7,8,9-tetrahydro-5H-pyrimido[5,4-d]azepine::CHEMBL1770374

SMILES: C(Cc1ncc2CCNCCc2n1)c1ccccc1

InChI Key: InChIKey=JLTBMCJFVPUFML-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50342542   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50342542 (2-phenethyl-6,7,8,9-tetrahydro-5H-pyrimido[5,4-d]a...) Show SMILES C(Cc1ncc2CCNCCc2n1)c1ccccc1 Show InChI InChI=1S/C16H19N3/c1-2-4-13(5-3-1)6-7-16-18-12-14-8-10-17-11-9-15(14)19-16/h1-5,12,17H,6-11H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at human 5HT2C receptor expressed in Swiss mouse 3T3 cells with low expression increase of fluorescence based calcium mobilization b...				Bioorg Med Chem Lett 21: 2715-20 (2011) Article DOI: 10.1016/j.bmcl.2010.11.120 BindingDB Entry DOI: 10.7270/Q2HD7VZZ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50342542 (2-phenethyl-6,7,8,9-tetrahydro-5H-pyrimido[5,4-d]a...) Show SMILES C(Cc1ncc2CCNCCc2n1)c1ccccc1 Show InChI InChI=1S/C16H19N3/c1-2-4-13(5-3-1)6-7-16-18-12-14-8-10-17-11-9-15(14)19-16/h1-5,12,17H,6-11H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	110	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Agonist activity at human 5HT2C receptor expressed in CHO-K1 cells assessed as increase of fluorescence based calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 21: 2715-20 (2011) Article DOI: 10.1016/j.bmcl.2010.11.120 BindingDB Entry DOI: 10.7270/Q2HD7VZZ
					More data for this Ligand-Target Pair