null

SMILES: CC(=O)C=C1C(=O)Nc2cc(OC(F)(F)F)ccc12

InChI Key: InChIKey=MGWOSFBTSQTSCX-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50342575   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-glutamine gamma-glutamyltransferase 2 (Homo sapiens (Human))	BDBM50342575 ((E)-3-(2-oxopropylidene)-6-(trifluoromethoxy)indol...) Show SMILES CC(=O)C=C1C(=O)Nc2cc(OC(F)(F)F)ccc12 |w:3.2| Show InChI InChI=1S/C12H8F3NO3/c1-6(17)4-9-8-3-2-7(19-12(13,14)15)5-10(8)16-11(9)18/h2-5H,1H3,(H,16,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Stanford University Curated by ChEMBL					Assay Description Inhibition of human transglutaminase 2 using ZGBC as a substrate after 30 to 60 mins by fluorometric assay				Bioorg Med Chem Lett 21: 2692-6 (2011) Article DOI: 10.1016/j.bmcl.2010.12.037 BindingDB Entry DOI: 10.7270/Q2CN7471
					More data for this Ligand-Target Pair
Protein-glutamine gamma-glutamyltransferase 2 (Homo sapiens (Human))	BDBM50342575 ((E)-3-(2-oxopropylidene)-6-(trifluoromethoxy)indol...) Show SMILES CC(=O)C=C1C(=O)Nc2cc(OC(F)(F)F)ccc12 |w:3.2| Show InChI InChI=1S/C12H8F3NO3/c1-6(17)4-9-8-3-2-7(19-12(13,14)15)5-10(8)16-11(9)18/h2-5H,1H3,(H,16,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Stanford University Curated by ChEMBL					Assay Description Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assay				Bioorg Med Chem Lett 21: 2692-6 (2011) Article DOI: 10.1016/j.bmcl.2010.12.037 BindingDB Entry DOI: 10.7270/Q2CN7471
					More data for this Ligand-Target Pair