BDBM50342703 CHEMBL1771104::rac-4-(3-(2-(3-(1-(5-chloropyrimidin-2-yl)piperidin-4-yl)propyl)cyclopropyl)propoxy)-N-cyclopropyl-2-fluorobenzamide

SMILES: Fc1cc(OCCCC2CC2CCCC2CCN(CC2)c2ncc(Cl)cn2)ccc1C(=O)NC1CC1

InChI Key: InChIKey=UKIRDFAQOIZTRR-UHFFFAOYSA-N

Data: 1 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50342703   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G-protein coupled receptor 119 (GPR119) (Homo sapiens (Human))	BDBM50342703 (CHEMBL1771104 | rac-4-(3-(2-(3-(1-(5-chloropyrimid...) Show SMILES Fc1cc(OCCCC2CC2CCCC2CCN(CC2)c2ncc(Cl)cn2)ccc1C(=O)NC1CC1 Show InChI InChI=1S/C28H36ClFN4O2/c29-22-17-31-28(32-18-22)34-12-10-19(11-13-34)3-1-4-20-15-21(20)5-2-14-36-24-8-9-25(26(30)16-24)27(35)33-23-6-7-23/h8-9,16-21,23H,1-7,10-15H2,(H,33,35)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.200	n/a	n/a	n/a	n/a
Merck& Co. Curated by ChEMBL					Assay Description Agonist activity at human GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase of intracellular cAMP accumulation after 60 mins ...				Bioorg Med Chem Lett 21: 2665-9 (2011) Article DOI: 10.1016/j.bmcl.2010.12.086 BindingDB Entry DOI: 10.7270/Q2M61KJV
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50342703 (CHEMBL1771104 | rac-4-(3-(2-(3-(1-(5-chloropyrimid...) Show SMILES Fc1cc(OCCCC2CC2CCCC2CCN(CC2)c2ncc(Cl)cn2)ccc1C(=O)NC1CC1 Show InChI InChI=1S/C28H36ClFN4O2/c29-22-17-31-28(32-18-22)34-12-10-19(11-13-34)3-1-4-20-15-21(20)5-2-14-36-24-8-9-25(26(30)16-24)27(35)33-23-6-7-23/h8-9,16-21,23H,1-7,10-15H2,(H,33,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck& Co. Curated by ChEMBL					Assay Description Inhibition of human ERG				Bioorg Med Chem Lett 21: 2665-9 (2011) Article DOI: 10.1016/j.bmcl.2010.12.086 BindingDB Entry DOI: 10.7270/Q2M61KJV
					More data for this Ligand-Target Pair
Glucose-dependent insulinotropic receptor (Mus musculus)	BDBM50342703 (CHEMBL1771104 | rac-4-(3-(2-(3-(1-(5-chloropyrimid...) Show SMILES Fc1cc(OCCCC2CC2CCCC2CCN(CC2)c2ncc(Cl)cn2)ccc1C(=O)NC1CC1 Show InChI InChI=1S/C28H36ClFN4O2/c29-22-17-31-28(32-18-22)34-12-10-19(11-13-34)3-1-4-20-15-21(20)5-2-14-36-24-8-9-25(26(30)16-24)27(35)33-23-6-7-23/h8-9,16-21,23H,1-7,10-15H2,(H,33,35)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.800	n/a	n/a	n/a	n/a
Merck& Co. Curated by ChEMBL					Assay Description Agonist activity at mouse GPR119 expressed in CHO cells co-expressing Galpha15 assessed as increase of intracellular cAMP accumulation after 60 mins ...				Bioorg Med Chem Lett 21: 2665-9 (2011) Article DOI: 10.1016/j.bmcl.2010.12.086 BindingDB Entry DOI: 10.7270/Q2M61KJV
					More data for this Ligand-Target Pair