BDBM50342891 6-(benzo[d][1,3]dioxol-5-yl)-N-((3-methylthiophen-2-yl)methyl)quinazolin-4-amine::CHEMBL1396654

SMILES: Cc1ccsc1CNc1ncnc2ccc(cc12)-c1ccc2OCOc2c1

InChI Key: InChIKey=OTKZKCGOQJKFMT-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50342891   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual-specificity tyrosine-regulated kinases 1B (Homo sapiens (Human))	BDBM50342891 (6-(benzo[d][1,3]dioxol-5-yl)-N-((3-methylthiophen-...) Show SMILES Cc1ccsc1CNc1ncnc2ccc(cc12)-c1ccc2OCOc2c1 Show InChI InChI=1S/C21H17N3O2S/c1-13-6-7-27-20(13)10-22-21-16-8-14(2-4-17(16)23-11-24-21)15-3-5-18-19(9-15)26-12-25-18/h2-9,11H,10,12H2,1H3,(H,22,23,24)	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	506	n/a	n/a	n/a	n/a	n/a	n/a
National Human Genome Research Institute Curated by ChEMBL					Assay Description Inhibition of Dyrk1B kinase using ATP as substrate by 33P radiolabelled kinase assay				Bioorg Med Chem Lett 21: 3152-8 (2011) Article DOI: 10.1016/j.bmcl.2011.02.114 BindingDB Entry DOI: 10.7270/Q2J67H83
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK2 (Homo sapiens (Human))	BDBM50342891 (6-(benzo[d][1,3]dioxol-5-yl)-N-((3-methylthiophen-...) Show SMILES Cc1ccsc1CNc1ncnc2ccc(cc12)-c1ccc2OCOc2c1 Show InChI InChI=1S/C21H17N3O2S/c1-13-6-7-27-20(13)10-22-21-16-8-14(2-4-17(16)23-11-24-21)15-3-5-18-19(9-15)26-12-25-18/h2-9,11H,10,12H2,1H3,(H,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Human Genome Research Institute Curated by ChEMBL					Assay Description Inhibition of Clk2 kinase using ATP as substrate by 33P radiolabelled kinase assay				Bioorg Med Chem Lett 21: 3152-8 (2011) Article DOI: 10.1016/j.bmcl.2011.02.114 BindingDB Entry DOI: 10.7270/Q2J67H83
					More data for this Ligand-Target Pair
Dual specificty protein kinase CLK1 (Homo sapiens (Human))	BDBM50342891 (6-(benzo[d][1,3]dioxol-5-yl)-N-((3-methylthiophen-...) Show SMILES Cc1ccsc1CNc1ncnc2ccc(cc12)-c1ccc2OCOc2c1 Show InChI InChI=1S/C21H17N3O2S/c1-13-6-7-27-20(13)10-22-21-16-8-14(2-4-17(16)23-11-24-21)15-3-5-18-19(9-15)26-12-25-18/h2-9,11H,10,12H2,1H3,(H,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
National Human Genome Research Institute Curated by ChEMBL					Assay Description Inhibition of Clk1 kinase using ATP as substrate by 33P radiolabelled kinase assay				Bioorg Med Chem Lett 21: 3152-8 (2011) Article DOI: 10.1016/j.bmcl.2011.02.114 BindingDB Entry DOI: 10.7270/Q2J67H83
					More data for this Ligand-Target Pair
Dual-specificity tyrosine-phosphorylation regulated kinase 1A (Homo sapiens (Human))	BDBM50342891 (6-(benzo[d][1,3]dioxol-5-yl)-N-((3-methylthiophen-...) Show SMILES Cc1ccsc1CNc1ncnc2ccc(cc12)-c1ccc2OCOc2c1 Show InChI InChI=1S/C21H17N3O2S/c1-13-6-7-27-20(13)10-22-21-16-8-14(2-4-17(16)23-11-24-21)15-3-5-18-19(9-15)26-12-25-18/h2-9,11H,10,12H2,1H3,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
National Human Genome Research Institute Curated by ChEMBL					Assay Description Inhibition of Dyrk1A kinase using ATP as substrate by 33P radiolabelled kinase assay				Bioorg Med Chem Lett 21: 3152-8 (2011) Article DOI: 10.1016/j.bmcl.2011.02.114 BindingDB Entry DOI: 10.7270/Q2J67H83
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK4 (Homo sapiens (Human))	BDBM50342891 (6-(benzo[d][1,3]dioxol-5-yl)-N-((3-methylthiophen-...) Show SMILES Cc1ccsc1CNc1ncnc2ccc(cc12)-c1ccc2OCOc2c1 Show InChI InChI=1S/C21H17N3O2S/c1-13-6-7-27-20(13)10-22-21-16-8-14(2-4-17(16)23-11-24-21)15-3-5-18-19(9-15)26-12-25-18/h2-9,11H,10,12H2,1H3,(H,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
National Human Genome Research Institute Curated by ChEMBL					Assay Description Inhibition of Clk4 kinase using ATP as substrate by 33P radiolabelled kinase assay				Bioorg Med Chem Lett 21: 3152-8 (2011) Article DOI: 10.1016/j.bmcl.2011.02.114 BindingDB Entry DOI: 10.7270/Q2J67H83
					More data for this Ligand-Target Pair
CDC2-like kinase 3 (CLK3) (Homo sapiens (Human))	BDBM50342891 (6-(benzo[d][1,3]dioxol-5-yl)-N-((3-methylthiophen-...) Show SMILES Cc1ccsc1CNc1ncnc2ccc(cc12)-c1ccc2OCOc2c1 Show InChI InChI=1S/C21H17N3O2S/c1-13-6-7-27-20(13)10-22-21-16-8-14(2-4-17(16)23-11-24-21)15-3-5-18-19(9-15)26-12-25-18/h2-9,11H,10,12H2,1H3,(H,22,23,24)	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.56E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Human Genome Research Institute Curated by ChEMBL					Assay Description Inhibition of Clk3 kinase using ATP as substrate by 33P radiolabelled kinase assay				Bioorg Med Chem Lett 21: 3152-8 (2011) Article DOI: 10.1016/j.bmcl.2011.02.114 BindingDB Entry DOI: 10.7270/Q2J67H83
					More data for this Ligand-Target Pair