BDBM50342918 6-(benzo[d][1,3]dioxol-5-yl)-N-((2-methylfuran-3-yl)methyl)quinazolin-4-amine::CHEMBL1476499

SMILES: Cc1occc1CNc1ncnc2ccc(cc12)-c1ccc2OCOc2c1

InChI Key: InChIKey=ONVZMCUWBPPGDN-UHFFFAOYSA-N

Data: 6 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50342918   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity protein kinase CLK2 (Homo sapiens (Human))	BDBM50342918 (6-(benzo[d][1,3]dioxol-5-yl)-N-((2-methylfuran-3-y...) Show SMILES Cc1occc1CNc1ncnc2ccc(cc12)-c1ccc2OCOc2c1 Show InChI InChI=1S/C21H17N3O3/c1-13-16(6-7-25-13)10-22-21-17-8-14(2-4-18(17)23-11-24-21)15-3-5-19-20(9-15)27-12-26-19/h2-9,11H,10,12H2,1H3,(H,22,23,24)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.73E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Human Genome Research Institute Curated by ChEMBL					Assay Description Inhibition of Clk2 kinase using ATP as substrate by 33P radiolabelled kinase assay				Bioorg Med Chem Lett 21: 3152-8 (2011) Article DOI: 10.1016/j.bmcl.2011.02.114 BindingDB Entry DOI: 10.7270/Q2J67H83
					More data for this Ligand-Target Pair
CDC2-like kinase 3 (CLK3) (Homo sapiens (Human))	BDBM50342918 (6-(benzo[d][1,3]dioxol-5-yl)-N-((2-methylfuran-3-y...) Show SMILES Cc1occc1CNc1ncnc2ccc(cc12)-c1ccc2OCOc2c1 Show InChI InChI=1S/C21H17N3O3/c1-13-16(6-7-25-13)10-22-21-17-8-14(2-4-18(17)23-11-24-21)15-3-5-19-20(9-15)27-12-26-19/h2-9,11H,10,12H2,1H3,(H,22,23,24)	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Human Genome Research Institute Curated by ChEMBL					Assay Description Inhibition of Clk3 kinase using ATP as substrate by 33P radiolabelled kinase assay				Bioorg Med Chem Lett 21: 3152-8 (2011) Article DOI: 10.1016/j.bmcl.2011.02.114 BindingDB Entry DOI: 10.7270/Q2J67H83
					More data for this Ligand-Target Pair
Dual specificty protein kinase CLK1 (Homo sapiens (Human))	BDBM50342918 (6-(benzo[d][1,3]dioxol-5-yl)-N-((2-methylfuran-3-y...) Show SMILES Cc1occc1CNc1ncnc2ccc(cc12)-c1ccc2OCOc2c1 Show InChI InChI=1S/C21H17N3O3/c1-13-16(6-7-25-13)10-22-21-17-8-14(2-4-18(17)23-11-24-21)15-3-5-19-20(9-15)27-12-26-19/h2-9,11H,10,12H2,1H3,(H,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	86	n/a	n/a	n/a	n/a	n/a	n/a
National Human Genome Research Institute Curated by ChEMBL					Assay Description Inhibition of Clk1 kinase using ATP as substrate by 33P radiolabelled kinase assay				Bioorg Med Chem Lett 21: 3152-8 (2011) Article DOI: 10.1016/j.bmcl.2011.02.114 BindingDB Entry DOI: 10.7270/Q2J67H83
					More data for this Ligand-Target Pair
Dual specificity protein kinase CLK4 (Homo sapiens (Human))	BDBM50342918 (6-(benzo[d][1,3]dioxol-5-yl)-N-((2-methylfuran-3-y...) Show SMILES Cc1occc1CNc1ncnc2ccc(cc12)-c1ccc2OCOc2c1 Show InChI InChI=1S/C21H17N3O3/c1-13-16(6-7-25-13)10-22-21-17-8-14(2-4-18(17)23-11-24-21)15-3-5-19-20(9-15)27-12-26-19/h2-9,11H,10,12H2,1H3,(H,22,23,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
National Human Genome Research Institute Curated by ChEMBL					Assay Description Inhibition of Clk4 kinase using ATP as substrate by 33P radiolabelled kinase assay				Bioorg Med Chem Lett 21: 3152-8 (2011) Article DOI: 10.1016/j.bmcl.2011.02.114 BindingDB Entry DOI: 10.7270/Q2J67H83
					More data for this Ligand-Target Pair
Dual-specificity tyrosine-phosphorylation regulated kinase 1A (Homo sapiens (Human))	BDBM50342918 (6-(benzo[d][1,3]dioxol-5-yl)-N-((2-methylfuran-3-y...) Show SMILES Cc1occc1CNc1ncnc2ccc(cc12)-c1ccc2OCOc2c1 Show InChI InChI=1S/C21H17N3O3/c1-13-16(6-7-25-13)10-22-21-17-8-14(2-4-18(17)23-11-24-21)15-3-5-19-20(9-15)27-12-26-19/h2-9,11H,10,12H2,1H3,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
National Human Genome Research Institute Curated by ChEMBL					Assay Description Inhibition of Dyrk1A kinase using ATP as substrate by 33P radiolabelled kinase assay				Bioorg Med Chem Lett 21: 3152-8 (2011) Article DOI: 10.1016/j.bmcl.2011.02.114 BindingDB Entry DOI: 10.7270/Q2J67H83
					More data for this Ligand-Target Pair
Dual-specificity tyrosine-regulated kinases 1B (Homo sapiens (Human))	BDBM50342918 (6-(benzo[d][1,3]dioxol-5-yl)-N-((2-methylfuran-3-y...) Show SMILES Cc1occc1CNc1ncnc2ccc(cc12)-c1ccc2OCOc2c1 Show InChI InChI=1S/C21H17N3O3/c1-13-16(6-7-25-13)10-22-21-17-8-14(2-4-18(17)23-11-24-21)15-3-5-19-20(9-15)27-12-26-19/h2-9,11H,10,12H2,1H3,(H,22,23,24)	UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	431	n/a	n/a	n/a	n/a	n/a	n/a
National Human Genome Research Institute Curated by ChEMBL					Assay Description Inhibition of Dyrk1B kinase using ATP as substrate by 33P radiolabelled kinase assay				Bioorg Med Chem Lett 21: 3152-8 (2011) Article DOI: 10.1016/j.bmcl.2011.02.114 BindingDB Entry DOI: 10.7270/Q2J67H83
					More data for this Ligand-Target Pair