BDBM50342999 CHEMBL1770984::N2-isopropyl-N2-methyl-6-(4-methylpiperazin-1-yl)pyrimidine-2,4-diamine

SMILES: CC(C)N(C)c1nc(N)cc(n1)N1CCN(C)CC1

InChI Key: InChIKey=NIDVTPNFWGIXKP-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50342999   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50342999 (CHEMBL1770984 | N2-isopropyl-N2-methyl-6-(4-methyl...) Show SMILES CC(C)N(C)c1nc(N)cc(n1)N1CCN(C)CC1 Show InChI InChI=1S/C13H24N6/c1-10(2)18(4)13-15-11(14)9-12(16-13)19-7-5-17(3)6-8-19/h9-10H,5-8H2,1-4H3,(H2,14,15,16)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	853	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor				Bioorg Med Chem Lett 21: 3113-6 (2011) Article DOI: 10.1016/j.bmcl.2011.03.017 BindingDB Entry DOI: 10.7270/Q24X5845
					More data for this Ligand-Target Pair