BDBM50343012 CHEMBL1770962::N2-isopropyl-4-(4-methylpiperazin-1-yl)pyridine-2,6-diamine

SMILES: CC(C)Nc1cc(cc(N)n1)N1CCN(C)CC1

InChI Key: InChIKey=LUKSYCWZFMYISW-UHFFFAOYSA-N

Data: 1 KI  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50343012   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50343012 (CHEMBL1770962 | N2-isopropyl-4-(4-methylpiperazin-...) Show SMILES CC(C)Nc1cc(cc(N)n1)N1CCN(C)CC1 Show InChI InChI=1S/C13H23N5/c1-10(2)15-13-9-11(8-12(14)16-13)18-6-4-17(3)5-7-18/h8-10H,4-7H2,1-3H3,(H3,14,15,16)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human histamine H4 receptor				Bioorg Med Chem Lett 21: 3113-6 (2011) Article DOI: 10.1016/j.bmcl.2011.03.017 BindingDB Entry DOI: 10.7270/Q24X5845
					More data for this Ligand-Target Pair
Histamine H4 receptor (Homo sapiens (Human))	BDBM50343012 (CHEMBL1770962 | N2-isopropyl-4-(4-methylpiperazin-...) Show SMILES CC(C)Nc1cc(cc(N)n1)N1CCN(C)CC1 Show InChI InChI=1S/C13H23N5/c1-10(2)15-13-9-11(8-12(14)16-13)18-6-4-17(3)5-7-18/h8-10H,4-7H2,1-3H3,(H3,14,15,16)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	533	n/a	n/a	n/a	n/a
Johnson& Johnson Pharmaceutical Research& Development Curated by ChEMBL					Assay Description Agonist activity at human histamine H4 receptor expressed in human SK-N-MC cells assessed as effect on forskolin-induced cAMP accumulation after 6 hr...				Bioorg Med Chem Lett 21: 3113-6 (2011) Article DOI: 10.1016/j.bmcl.2011.03.017 BindingDB Entry DOI: 10.7270/Q24X5845
					More data for this Ligand-Target Pair