Found 4 hits for monomerid = 50343050 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Matrix metalloproteinase-9
(Homo sapiens (Human)) | BDBM50343050
(4-(4-(4-(4-(dimethylamino)benzoyl)piperidin-1-yl)p...)Show SMILES CN(C)c1ccc(cc1)C(=O)C1CCN(CC1)c1ccc(cc1)S(=O)(=O)C1(CCOCC1)C(=O)NO Show InChI InChI=1S/C26H33N3O6S/c1-28(2)21-5-3-19(4-6-21)24(30)20-11-15-29(16-12-20)22-7-9-23(10-8-22)36(33,34)26(25(31)27-32)13-17-35-18-14-26/h3-10,20,32H,11-18H2,1-2H3,(H,27,31) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Inhibition of human MMP9 |
Bioorg Med Chem Lett 21: 2823-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.03.095 BindingDB Entry DOI: 10.7270/Q2CF9QD0 |
More data for this Ligand-Target Pair | |
Collagenase 3
(Homo sapiens (Human)) | BDBM50343050
(4-(4-(4-(4-(dimethylamino)benzoyl)piperidin-1-yl)p...)Show SMILES CN(C)c1ccc(cc1)C(=O)C1CCN(CC1)c1ccc(cc1)S(=O)(=O)C1(CCOCC1)C(=O)NO Show InChI InChI=1S/C26H33N3O6S/c1-28(2)21-5-3-19(4-6-21)24(30)20-11-15-29(16-12-20)22-7-9-23(10-8-22)36(33,34)26(25(31)27-32)13-17-35-18-14-26/h3-10,20,32H,11-18H2,1-2H3,(H,27,31) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Inhibition of human MMP13 |
Bioorg Med Chem Lett 21: 2823-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.03.095 BindingDB Entry DOI: 10.7270/Q2CF9QD0 |
More data for this Ligand-Target Pair | |
Neutrophil collagenase
(Homo sapiens (Human)) | BDBM50343050
(4-(4-(4-(4-(dimethylamino)benzoyl)piperidin-1-yl)p...)Show SMILES CN(C)c1ccc(cc1)C(=O)C1CCN(CC1)c1ccc(cc1)S(=O)(=O)C1(CCOCC1)C(=O)NO Show InChI InChI=1S/C26H33N3O6S/c1-28(2)21-5-3-19(4-6-21)24(30)20-11-15-29(16-12-20)22-7-9-23(10-8-22)36(33,34)26(25(31)27-32)13-17-35-18-14-26/h3-10,20,32H,11-18H2,1-2H3,(H,27,31) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Inhibition of human MMP8 |
Bioorg Med Chem Lett 21: 2823-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.03.095 BindingDB Entry DOI: 10.7270/Q2CF9QD0 |
More data for this Ligand-Target Pair | |
72 kDa type IV collagenase
(Homo sapiens (Human)) | BDBM50343050
(4-(4-(4-(4-(dimethylamino)benzoyl)piperidin-1-yl)p...)Show SMILES CN(C)c1ccc(cc1)C(=O)C1CCN(CC1)c1ccc(cc1)S(=O)(=O)C1(CCOCC1)C(=O)NO Show InChI InChI=1S/C26H33N3O6S/c1-28(2)21-5-3-19(4-6-21)24(30)20-11-15-29(16-12-20)22-7-9-23(10-8-22)36(33,34)26(25(31)27-32)13-17-35-18-14-26/h3-10,20,32H,11-18H2,1-2H3,(H,27,31) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc.
Curated by ChEMBL
| Assay Description Inhibition of human MMP2 |
Bioorg Med Chem Lett 21: 2823-5 (2011)
Article DOI: 10.1016/j.bmcl.2011.03.095 BindingDB Entry DOI: 10.7270/Q2CF9QD0 |
More data for this Ligand-Target Pair | |