BDBM50343106 CHEMBL1771241::N-(3-cyclopropylphenyl)-2-(pyridin-3-yl)-4-o-tolyl-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxamide

SMILES: Cc1ccccc1-c1nc(nc2CCN(Cc12)C(=O)Nc1cccc(c1)C1CC1)-c1cccnc1

InChI Key: InChIKey=BMESARUQEQBODD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50343106   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
P2Y purinoceptor 14 (Mus musculus)	BDBM50343106 (CHEMBL1771241 | N-(3-cyclopropylphenyl)-2-(pyridin...) Show SMILES Cc1ccccc1-c1nc(nc2CCN(Cc12)C(=O)Nc1cccc(c1)C1CC1)-c1cccnc1 Show InChI InChI=1S/C29H27N5O/c1-19-6-2-3-10-24(19)27-25-18-34(29(35)31-23-9-4-7-21(16-23)20-11-12-20)15-13-26(25)32-28(33-27)22-8-5-14-30-17-22/h2-10,14,16-17,20H,11-13,15,18H2,1H3,(H,31,35)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Center for Therapeutic Research Curated by ChEMBL					Assay Description Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...				Bioorg Med Chem Lett 21: 2832-5 (2011) Article DOI: 10.1016/j.bmcl.2011.03.084 BindingDB Entry DOI: 10.7270/Q20865N7
					More data for this Ligand-Target Pair