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SMILES: Cc1ccccc1-c1cccc(CNc2ccc(CCC(O)=O)cc2)c1

InChI Key: InChIKey=RUPXKSLKGSSZCP-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50343141   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50343141 (3-(4(2'-Methylbiphenyl-3-ylmethylamino)phenyl)prop...) Show SMILES Cc1ccccc1-c1cccc(CNc2ccc(CCC(O)=O)cc2)c1 Show InChI InChI=1S/C23H23NO2/c1-17-5-2-3-8-22(17)20-7-4-6-19(15-20)16-24-21-12-9-18(10-13-21)11-14-23(25)26/h2-10,12-13,15,24H,11,14,16H2,1H3,(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	5.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Displacement of 3-(2-Fluoro-4-((2'-methyl-4'-(2-(2-((7-nitrobenzo[c][1,2,5]-oxadiazol-4-yl)amino)ethoxy)ethoxy)-[1,1'-biphenyl]-3-yl)-methoxy)phenyl)...				J Med Chem 59: 4849-58 (2016) BindingDB Entry DOI: 10.7270/Q24T6M9W
					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Mus musculus)	BDBM50343141 (3-(4(2'-Methylbiphenyl-3-ylmethylamino)phenyl)prop...) Show SMILES Cc1ccccc1-c1cccc(CNc2ccc(CCC(O)=O)cc2)c1 Show InChI InChI=1S/C23H23NO2/c1-17-5-2-3-8-22(17)20-7-4-6-19(15-20)16-24-21-12-9-18(10-13-21)11-14-23(25)26/h2-10,12-13,15,24H,11,14,16H2,1H3,(H,25,26)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	19	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Activation of FFA1 in mouse islets assessed as glucose-dependent insulin secretion				ACS Med Chem Lett 1: 345-349 (2010) Article DOI: 10.1021/ml100106c BindingDB Entry DOI: 10.7270/Q2M045RN
					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50343141 (3-(4(2'-Methylbiphenyl-3-ylmethylamino)phenyl)prop...) Show SMILES Cc1ccccc1-c1cccc(CNc2ccc(CCC(O)=O)cc2)c1 Show InChI InChI=1S/C23H23NO2/c1-17-5-2-3-8-22(17)20-7-4-6-19(15-20)16-24-21-12-9-18(10-13-21)11-14-23(25)26/h2-10,12-13,15,24H,11,14,16H2,1H3,(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	18.6	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at human FFA1 receptor expressed in human 1321N1 cells assessed as calcium mobilization by fluorescence spectrophotometry				J Med Chem 54: 6691-703 (2011) Article DOI: 10.1021/jm2005699 BindingDB Entry DOI: 10.7270/Q25T3MRW
					More data for this Ligand-Target Pair
Free fatty acid receptor 4 (Homo sapiens (Human))	BDBM50343141 (3-(4(2'-Methylbiphenyl-3-ylmethylamino)phenyl)prop...) Show SMILES Cc1ccccc1-c1cccc(CNc2ccc(CCC(O)=O)cc2)c1 Show InChI InChI=1S/C23H23NO2/c1-17-5-2-3-8-22(17)20-7-4-6-19(15-20)16-24-21-12-9-18(10-13-21)11-14-23(25)26/h2-10,12-13,15,24H,11,14,16H2,1H3,(H,25,26)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.31E+3	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at GPR120 assessed as stimulation of calcium mobilization				J Med Chem 55: 6624-8 (2012) Article DOI: 10.1021/jm3002026 BindingDB Entry DOI: 10.7270/Q2P84D1H
					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50343141 (3-(4(2'-Methylbiphenyl-3-ylmethylamino)phenyl)prop...) Show SMILES Cc1ccccc1-c1cccc(CNc2ccc(CCC(O)=O)cc2)c1 Show InChI InChI=1S/C23H23NO2/c1-17-5-2-3-8-22(17)20-7-4-6-19(15-20)16-24-21-12-9-18(10-13-21)11-14-23(25)26/h2-10,12-13,15,24H,11,14,16H2,1H3,(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	12.9	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at FFAR1 expressed in HEK 293 cells assessed as beta-arrestin recruitment after 30 mins by BRET assay				J Med Chem 55: 4511-5 (2012) Article DOI: 10.1021/jm300215x BindingDB Entry DOI: 10.7270/Q21Z45P4
					More data for this Ligand-Target Pair
Free fatty acid receptor 4 (Homo sapiens (Human))	BDBM50343141 (3-(4(2'-Methylbiphenyl-3-ylmethylamino)phenyl)prop...) Show SMILES Cc1ccccc1-c1cccc(CNc2ccc(CCC(O)=O)cc2)c1 Show InChI InChI=1S/C23H23NO2/c1-17-5-2-3-8-22(17)20-7-4-6-19(15-20)16-24-21-12-9-18(10-13-21)11-14-23(25)26/h2-10,12-13,15,24H,11,14,16H2,1H3,(H,25,26)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.31E+3	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at GPR120 expressed in HEK 293 cells assessed as beta-arrestin recruitment after 5 mins by BRET assay				J Med Chem 55: 4511-5 (2012) Article DOI: 10.1021/jm300215x BindingDB Entry DOI: 10.7270/Q21Z45P4
					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50343141 (3-(4(2'-Methylbiphenyl-3-ylmethylamino)phenyl)prop...) Show SMILES Cc1ccccc1-c1cccc(CNc2ccc(CCC(O)=O)cc2)c1 Show InChI InChI=1S/C23H23NO2/c1-17-5-2-3-8-22(17)20-7-4-6-19(15-20)16-24-21-12-9-18(10-13-21)11-14-23(25)26/h2-10,12-13,15,24H,11,14,16H2,1H3,(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	11	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at human C-terminal eYFP-tagged FFA1 receptor expressed in HEK-293 cells assessed as beta-arrestin2 recruitment incubated for 5 mins...				J Med Chem 59: 4849-58 (2016) BindingDB Entry DOI: 10.7270/Q24T6M9W
					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50343141 (3-(4(2'-Methylbiphenyl-3-ylmethylamino)phenyl)prop...) Show SMILES Cc1ccccc1-c1cccc(CNc2ccc(CCC(O)=O)cc2)c1 Show InChI InChI=1S/C23H23NO2/c1-17-5-2-3-8-22(17)20-7-4-6-19(15-20)16-24-21-12-9-18(10-13-21)11-14-23(25)26/h2-10,12-13,15,24H,11,14,16H2,1H3,(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	18.6	n/a	n/a	n/a	n/a
University of Southern Denmark Curated by ChEMBL					Assay Description Agonist activity at human GPR40 expressed in Flp-InTM T-RexTM HEK293 cells assessed as stimulation of calcium mobilization				J Med Chem 55: 6624-8 (2012) Article DOI: 10.1021/jm3002026 BindingDB Entry DOI: 10.7270/Q2P84D1H
					More data for this Ligand-Target Pair