BDBM50343199 CHEMBL1773601::N-(6-(3-(4-Methoxyphenylsulfonamido)phenyl)benzo[d]thiazol-2-yl)acetamide

SMILES: COc1ccc(cc1)S(=O)(=O)Nc1cccc(c1)-c1ccc2nc(NC(C)=O)sc2c1

InChI Key: InChIKey=AJYCJBFSBQHKOS-UHFFFAOYSA-N

Data: 1 KI  2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50343199   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50343199 (CHEMBL1773601 | N-(6-(3-(4-Methoxyphenylsulfonamid...) Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1cccc(c1)-c1ccc2nc(NC(C)=O)sc2c1 Show InChI InChI=1S/C22H19N3O4S2/c1-14(26)23-22-24-20-11-6-16(13-21(20)30-22)15-4-3-5-17(12-15)25-31(27,28)19-9-7-18(29-2)8-10-19/h3-13,25H,1-2H3,(H,23,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human PI3Kalpha expressed in Sf9 cells				J Med Chem 54: 1789-811 (2011) Article DOI: 10.1021/jm1014605 BindingDB Entry DOI: 10.7270/Q2TH8N1K
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase mTOR (Homo sapiens (Human))	BDBM50343199 (CHEMBL1773601 | N-(6-(3-(4-Methoxyphenylsulfonamid...) Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1cccc(c1)-c1ccc2nc(NC(C)=O)sc2c1 Show InChI InChI=1S/C22H19N3O4S2/c1-14(26)23-22-24-20-11-6-16(13-21(20)30-22)15-4-3-5-17(12-15)25-31(27,28)19-9-7-18(29-2)8-10-19/h3-13,25H,1-2H3,(H,23,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of mTOR assessed as inhibition of 4EBP1 phosphorylation by TR-FRET assay				J Med Chem 54: 1789-811 (2011) Article DOI: 10.1021/jm1014605 BindingDB Entry DOI: 10.7270/Q2TH8N1K
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50343199 (CHEMBL1773601 | N-(6-(3-(4-Methoxyphenylsulfonamid...) Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1cccc(c1)-c1ccc2nc(NC(C)=O)sc2c1 Show InChI InChI=1S/C22H19N3O4S2/c1-14(26)23-22-24-20-11-6-16(13-21(20)30-22)15-4-3-5-17(12-15)25-31(27,28)19-9-7-18(29-2)8-10-19/h3-13,25H,1-2H3,(H,23,24,26)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of AKT phosphorylation at S473 in human U-87MG cells at 5 mM after 2 hrs				J Med Chem 54: 1789-811 (2011) Article DOI: 10.1021/jm1014605 BindingDB Entry DOI: 10.7270/Q2TH8N1K
					More data for this Ligand-Target Pair