BDBM50343389 6-(2-(4-fluorophenylamino)-4-(4-(pyrrolidin-1-ylsulfonyl)phenyl)thiazol-3(2H)-yl)hexan-1-ol::CHEMBL1774934

SMILES: OCCCCCCN1C(Nc2ccc(F)cc2)SC=C1c1ccc(cc1)S(=O)(=O)N1CCCC1

InChI Key: InChIKey=FJBPTHKTZDLUSR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50343389   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Uracil-DNA glycosylase (Vaccinia virus (strain Western Reserve) (VACV) (Va...)	BDBM50343389 (6-(2-(4-fluorophenylamino)-4-(4-(pyrrolidin-1-ylsu...) Show SMILES OCCCCCCN1C(Nc2ccc(F)cc2)SC=C1c1ccc(cc1)S(=O)(=O)N1CCCC1 |c:19| Show InChI InChI=1S/C25H32FN3O3S2/c26-21-9-11-22(12-10-21)27-25-29(17-3-1-2-6-18-30)24(19-33-25)20-7-13-23(14-8-20)34(31,32)28-15-4-5-16-28/h7-14,19,25,27,30H,1-6,15-18H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...				J Med Chem 54: 3260-7 (2011) Article DOI: 10.1021/jm101554k BindingDB Entry DOI: 10.7270/Q2J103GF
					More data for this Ligand-Target Pair