BDBM50343392 4-(6-chloro-3-(2,3-dihydrobenzo[b][1,4]dioxin-6-ylamino)imidazo[1,2-a]pyridin-2-yl)-2-methoxyphenol::CHEMBL1454891

SMILES: COc1cc(ccc1O)-c1nc2ccc(Cl)cn2c1Nc1ccc2OCCOc2c1

InChI Key: InChIKey=FORWZMHKVUGVDT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50343392   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Uracil-DNA glycosylase (Vaccinia virus (strain Western Reserve) (VACV) (Va...)	BDBM50343392 (4-(6-chloro-3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl...) Show SMILES COc1cc(ccc1O)-c1nc2ccc(Cl)cn2c1Nc1ccc2OCCOc2c1 Show InChI InChI=1S/C22H18ClN3O4/c1-28-18-10-13(2-5-16(18)27)21-22(26-12-14(23)3-7-20(26)25-21)24-15-4-6-17-19(11-15)30-9-8-29-17/h2-7,10-12,24,27H,8-9H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...				J Med Chem 54: 3260-7 (2011) Article DOI: 10.1021/jm101554k BindingDB Entry DOI: 10.7270/Q2J103GF
					More data for this Ligand-Target Pair