BDBM50343398 5-bromo-2-(5-(o-tolylamino)imidazo[2,1-b]thiazol-6-yl)phenol::CHEMBL1436172

SMILES: Cc1ccccc1Nc1c(nc2sccn12)-c1ccc(Br)cc1O

InChI Key: InChIKey=APOWOOUBHQIDMK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50343398   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Uracil-DNA glycosylase (Vaccinia virus (strain Western Reserve) (VACV) (Va...)	BDBM50343398 (5-bromo-2-(5-(o-tolylamino)imidazo[2,1-b]thiazol-6...) Show SMILES Cc1ccccc1Nc1c(nc2sccn12)-c1ccc(Br)cc1O Show InChI InChI=1S/C18H14BrN3OS/c1-11-4-2-3-5-14(11)20-17-16(21-18-22(17)8-9-24-18)13-7-6-12(19)10-15(13)23/h2-10,20,23H,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...				J Med Chem 54: 3260-7 (2011) Article DOI: 10.1021/jm101554k BindingDB Entry DOI: 10.7270/Q2J103GF
					More data for this Ligand-Target Pair