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BDBM50343402 CHEMBL1599158::N-(4-(dimethylamino)phenyl)-2-(4-(furan-2-yl)-6-(trifluoromethyl)pyrimidin-2-ylthio)acetamide

SMILES: CN(C)c1ccc(NC(=O)CSc2nc(cc(n2)C(F)(F)F)-c2ccco2)cc1

InChI Key: InChIKey=KCKJRQJJSBPZAL-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50343402   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Uracil-DNA glycosylase


(Vaccinia virus (strain Western Reserve) (VACV) (Va...)		BDBM50343402
PNG
(CHEMBL1599158 | N-(4-(dimethylamino)phenyl)-2-(4-(...)
Show SMILES CN(C)c1ccc(NC(=O)CSc2nc(cc(n2)C(F)(F)F)-c2ccco2)cc1
Show InChI InChI=1S/C19H17F3N4O2S/c1-26(2)13-7-5-12(6-8-13)23-17(27)11-29-18-24-14(15-4-3-9-28-15)10-16(25-18)19(20,21)22/h3-10H,11H2,1-2H3,(H,23,27)
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.40E+5n/an/an/an/an/an/a



University of Pennsylvania

Curated by ChEMBL


Assay Description
Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...

J Med Chem 54: 3260-7 (2011)


Article DOI: 10.1021/jm101554k
BindingDB Entry DOI: 10.7270/Q2J103GF
More data for this
Ligand-Target Pair