BDBM50343406 2-(2,4-dimethoxyphenylamino)-N-(3-(4-(2-fluorophenyl)piperazin-1-yl)propyl)quinoline-4-carboxamide::CHEMBL1322766

SMILES: COc1ccc(Nc2cc(C(=O)NCCCN3CCN(CC3)c3ccccc3F)c3ccccc3n2)c(OC)c1

InChI Key: InChIKey=AUQXOOLYTXAZOD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50343406   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Uracil-DNA glycosylase (Vaccinia virus (strain Western Reserve) (VACV) (Va...)	BDBM50343406 (2-(2,4-dimethoxyphenylamino)-N-(3-(4-(2-fluorophen...) Show SMILES COc1ccc(Nc2cc(C(=O)NCCCN3CCN(CC3)c3ccccc3F)c3ccccc3n2)c(OC)c1 Show InChI InChI=1S/C31H34FN5O3/c1-39-22-12-13-27(29(20-22)40-2)35-30-21-24(23-8-3-5-10-26(23)34-30)31(38)33-14-7-15-36-16-18-37(19-17-36)28-11-6-4-9-25(28)32/h3-6,8-13,20-21H,7,14-19H2,1-2H3,(H,33,38)(H,34,35)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...				J Med Chem 54: 3260-7 (2011) Article DOI: 10.1021/jm101554k BindingDB Entry DOI: 10.7270/Q2J103GF
					More data for this Ligand-Target Pair