BDBM50343408 2-cyclohexyl-3-oxo-N-(3,4,5-trimethoxyphenyl)isoindoline-4-carboxamide::CHEMBL1409096

SMILES: COc1cc(NC(=O)c2cccc3CN(C4CCCCC4)C(=O)c23)cc(OC)c1OC

InChI Key: InChIKey=BSPFBFCJTOQUKF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50343408   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Uracil-DNA glycosylase (Vaccinia virus (strain Western Reserve) (VACV) (Va...)	BDBM50343408 (2-cyclohexyl-3-oxo-N-(3,4,5-trimethoxyphenyl)isoin...) Show SMILES COc1cc(NC(=O)c2cccc3CN(C4CCCCC4)C(=O)c23)cc(OC)c1OC Show InChI InChI=1S/C24H28N2O5/c1-29-19-12-16(13-20(30-2)22(19)31-3)25-23(27)18-11-7-8-15-14-26(24(28)21(15)18)17-9-5-4-6-10-17/h7-8,11-13,17H,4-6,9-10,14H2,1-3H3,(H,25,27)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...				J Med Chem 54: 3260-7 (2011) Article DOI: 10.1021/jm101554k BindingDB Entry DOI: 10.7270/Q2J103GF
					More data for this Ligand-Target Pair