BDBM50343412 4-[5-(4-bromophenyl)-4-phenyl-1H-imidazol-2-yl]-2,6-dimethoxyphenol::CHEMBL1406781

SMILES: COc1cc(cc(OC)c1O)-c1nc(c([nH]1)-c1ccc(Br)cc1)-c1ccccc1

InChI Key: InChIKey=ISRGEWIJLLSRJY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50343412   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Uracil-DNA glycosylase (Vaccinia virus (strain Western Reserve) (VACV) (Va...)	BDBM50343412 (4-[5-(4-bromophenyl)-4-phenyl-1H-imidazol-2-yl]-2,...) Show SMILES COc1cc(cc(OC)c1O)-c1nc(c([nH]1)-c1ccc(Br)cc1)-c1ccccc1 Show InChI InChI=1S/C23H19BrN2O3/c1-28-18-12-16(13-19(29-2)22(18)27)23-25-20(14-6-4-3-5-7-14)21(26-23)15-8-10-17(24)11-9-15/h3-13,27H,1-2H3,(H,25,26)	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.12E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...				J Med Chem 54: 3260-7 (2011) Article DOI: 10.1021/jm101554k BindingDB Entry DOI: 10.7270/Q2J103GF
					More data for this Ligand-Target Pair