BDBM50343433 CHEMBL1773289::tert-butyl 4-(3,6-dimethyl-1-(4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yloxy)piperidine-1-carboxylate

SMILES: Cc1nn(-c2ccc(cc2)S(C)(=O)=O)c2nc(C)nc(OC3CCN(CC3)C(=O)OC(C)(C)C)c12

InChI Key: InChIKey=JEHGKJLXZUARCY-UHFFFAOYSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50343433   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G-protein coupled receptor 119 (GPR119) (Homo sapiens (Human))	BDBM50343433 (CHEMBL1773289 | tert-butyl 4-(3,6-dimethyl-1-(4-(m...) Show SMILES Cc1nn(-c2ccc(cc2)S(C)(=O)=O)c2nc(C)nc(OC3CCN(CC3)C(=O)OC(C)(C)C)c12 Show InChI InChI=1S/C24H31N5O5S/c1-15-20-21(29(27-15)17-7-9-19(10-8-17)35(6,31)32)25-16(2)26-22(20)33-18-11-13-28(14-12-18)23(30)34-24(3,4)5/h7-10,18H,11-14H2,1-6H3	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	116	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Agonist activity at human GPR119 by melanophore assay				Bioorg Med Chem Lett 21: 3134-41 (2011) Article DOI: 10.1016/j.bmcl.2011.03.007 BindingDB Entry DOI: 10.7270/Q24T6JQF
					More data for this Ligand-Target Pair