BDBM50343667 4-(4-chlorophenyl)-N-(piperidin-4-yl)pyrimidin-2-amine::CHEMBL1775219

SMILES: Clc1ccc(cc1)-c1ccnc(NC2CCNCC2)n1

InChI Key: InChIKey=CRLCYUHWQKIZTC-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50343667   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inhibitor of nuclear factor kappa-B kinase subunit beta (Homo sapiens (Human))	BDBM50343667 (4-(4-chlorophenyl)-N-(piperidin-4-yl)pyrimidin-2-a...) Show SMILES Clc1ccc(cc1)-c1ccnc(NC2CCNCC2)n1 Show InChI InChI=1S/C15H17ClN4/c16-12-3-1-11(2-4-12)14-7-10-18-15(20-14)19-13-5-8-17-9-6-13/h1-4,7,10,13,17H,5-6,8-9H2,(H,18,19,20)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of IKK2 using 5-FAM-GRHDSGLDSMK-NH2 as substrate by TR-FRET assay				Bioorg Med Chem Lett 21: 3002-6 (2011) Article DOI: 10.1016/j.bmcl.2011.03.044 BindingDB Entry DOI: 10.7270/Q22V2GDS
					More data for this Ligand-Target Pair