BDBM50343669 4-(4-(4-chlorophenyl)pyrimidin-2-ylamino)piperidine-1-sulfonamide::CHEMBL1775233

SMILES: NS(=O)(=O)N1CCC(CC1)Nc1nccc(n1)-c1ccc(Cl)cc1

InChI Key: InChIKey=GYDNRCSRFZVIPA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50343669   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inhibitor of nuclear factor kappa-B kinase subunit beta (Homo sapiens (Human))	BDBM50343669 (4-(4-(4-chlorophenyl)pyrimidin-2-ylamino)piperidin...) Show SMILES NS(=O)(=O)N1CCC(CC1)Nc1nccc(n1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C15H18ClN5O2S/c16-12-3-1-11(2-4-12)14-5-8-18-15(20-14)19-13-6-9-21(10-7-13)24(17,22)23/h1-5,8,13H,6-7,9-10H2,(H2,17,22,23)(H,18,19,20)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of IKK2 using 5-FAM-GRHDSGLDSMK-NH2 as substrate by TR-FRET assay				Bioorg Med Chem Lett 21: 3002-6 (2011) Article DOI: 10.1016/j.bmcl.2011.03.044 BindingDB Entry DOI: 10.7270/Q22V2GDS
					More data for this Ligand-Target Pair