BDBM50343670 4-(4-chlorophenyl)-N-(1-methylpiperidin-4-yl)pyrimidin-2-amine::CHEMBL1773326

SMILES: CN1CCC(CC1)Nc1nccc(n1)-c1ccc(Cl)cc1

InChI Key: InChIKey=CUSQCUQKTMXNGI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50343670   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inhibitor of nuclear factor kappa-B kinase subunit beta (Homo sapiens (Human))	BDBM50343670 (4-(4-chlorophenyl)-N-(1-methylpiperidin-4-yl)pyrim...) Show SMILES CN1CCC(CC1)Nc1nccc(n1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C16H19ClN4/c1-21-10-7-14(8-11-21)19-16-18-9-6-15(20-16)12-2-4-13(17)5-3-12/h2-6,9,14H,7-8,10-11H2,1H3,(H,18,19,20)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.97E+4	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of IKK2 using 5-FAM-GRHDSGLDSMK-NH2 as substrate by TR-FRET assay				Bioorg Med Chem Lett 21: 3002-6 (2011) Article DOI: 10.1016/j.bmcl.2011.03.044 BindingDB Entry DOI: 10.7270/Q22V2GDS
					More data for this Ligand-Target Pair