BDBM50343671 4-(4-(morpholinosulfonyl)phenyl)-N-(piperidin-4-yl)pyrimidin-2-amine::CHEMBL1773327

SMILES: O=S(=O)(N1CCOCC1)c1ccc(cc1)-c1ccnc(NC2CCNCC2)n1

InChI Key: InChIKey=IEVVEZPHOGJDKA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50343671   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inhibitor of nuclear factor kappa-B kinase subunit beta (Homo sapiens (Human))	BDBM50343671 (4-(4-(morpholinosulfonyl)phenyl)-N-(piperidin-4-yl...) Show SMILES O=S(=O)(N1CCOCC1)c1ccc(cc1)-c1ccnc(NC2CCNCC2)n1 Show InChI InChI=1S/C19H25N5O3S/c25-28(26,24-11-13-27-14-12-24)17-3-1-15(2-4-17)18-7-10-21-19(23-18)22-16-5-8-20-9-6-16/h1-4,7,10,16,20H,5-6,8-9,11-14H2,(H,21,22,23)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
Korea Institute of Science and Technology Curated by ChEMBL					Assay Description Inhibition of IKK2 using 5-FAM-GRHDSGLDSMK-NH2 as substrate by TR-FRET assay				Bioorg Med Chem Lett 21: 3002-6 (2011) Article DOI: 10.1016/j.bmcl.2011.03.044 BindingDB Entry DOI: 10.7270/Q22V2GDS
					More data for this Ligand-Target Pair