BDBM50344061 8-hydroxy-3-(4'-hydroxy)phenylcoumarin::CHEMBL1777848

SMILES: Oc1ccc(cc1)-c1cc2cccc(O)c2oc1=O

InChI Key: InChIKey=HXOYIYQATHNBKZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344061   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosinase (Agaricus bisporus (Common mushroom))	BDBM50344061 (8-hydroxy-3-(4'-hydroxy)phenylcoumarin | CHEMBL177...) Show SMILES Oc1ccc(cc1)-c1cc2cccc(O)c2oc1=O Show InChI InChI=1S/C15H10O4/c16-11-6-4-9(5-7-11)12-8-10-2-1-3-13(17)14(10)19-15(12)18/h1-8,16-17H	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+6	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Santiago de Compostela Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase using L-3,4- dihydroxyphenylalanine as substrate measured for 5 mins by spectrophotometric analysis				Bioorg Med Chem Lett 21: 3342-5 (2011) Article DOI: 10.1016/j.bmcl.2011.04.012 BindingDB Entry DOI: 10.7270/Q2QF8T68
					More data for this Ligand-Target Pair