BDBM50344062 6-Bromo-8-hydroxy-3-(4'-hydroxyphenyl)coumarin::CHEMBL1777849

SMILES: Oc1ccc(cc1)-c1cc2cc(Br)cc(O)c2oc1=O

InChI Key: InChIKey=JRNZENXEHYOMCY-UHFFFAOYSA-N

Data: 1 KI  3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50344062   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosinase (Agaricus bisporus (Common mushroom))	BDBM50344062 (6-Bromo-8-hydroxy-3-(4'-hydroxyphenyl)coumarin | C...) Show SMILES Oc1ccc(cc1)-c1cc2cc(Br)cc(O)c2oc1=O Show InChI InChI=1S/C15H9BrO4/c16-10-5-9-6-12(8-1-3-11(17)4-2-8)15(19)20-14(9)13(18)7-10/h1-7,17-18H	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.89E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Santiago de Compostela Curated by ChEMBL					Assay Description Non-competitive inhibition of mushroom tyrosinase using L-3,4- dihydroxyphenylalanine as substrate by Lineweaver-Burk double reciprocal plot analysis				Bioorg Med Chem Lett 21: 3342-5 (2011) Article DOI: 10.1016/j.bmcl.2011.04.012 BindingDB Entry DOI: 10.7270/Q2QF8T68
					More data for this Ligand-Target Pair
Amine oxidase (flavin-containing) A (Homo sapiens (Human))	BDBM50344062 (6-Bromo-8-hydroxy-3-(4'-hydroxyphenyl)coumarin | C...) Show SMILES Oc1ccc(cc1)-c1cc2cc(Br)cc(O)c2oc1=O Show InChI InChI=1S/C15H9BrO4/c16-10-5-9-6-12(8-1-3-11(17)4-2-8)15(19)20-14(9)13(18)7-10/h1-7,17-18H	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Santiago de Compostela Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-A using p-tyramine substrate by flurometric method				Bioorg Med Chem Lett 21: 4224-7 (2011) Article DOI: 10.1016/j.bmcl.2011.05.074 BindingDB Entry DOI: 10.7270/Q27H1JX2
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50344062 (6-Bromo-8-hydroxy-3-(4'-hydroxyphenyl)coumarin | C...) Show SMILES Oc1ccc(cc1)-c1cc2cc(Br)cc(O)c2oc1=O Show InChI InChI=1S/C15H9BrO4/c16-10-5-9-6-12(8-1-3-11(17)4-2-8)15(19)20-14(9)13(18)7-10/h1-7,17-18H	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.69E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Santiago de Compostela Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-B using p-tyramine substrate by flurometric method				Bioorg Med Chem Lett 21: 4224-7 (2011) Article DOI: 10.1016/j.bmcl.2011.05.074 BindingDB Entry DOI: 10.7270/Q27H1JX2
					More data for this Ligand-Target Pair
Tyrosinase (Agaricus bisporus (Common mushroom))	BDBM50344062 (6-Bromo-8-hydroxy-3-(4'-hydroxyphenyl)coumarin | C...) Show SMILES Oc1ccc(cc1)-c1cc2cc(Br)cc(O)c2oc1=O Show InChI InChI=1S/C15H9BrO4/c16-10-5-9-6-12(8-1-3-11(17)4-2-8)15(19)20-14(9)13(18)7-10/h1-7,17-18H	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.15E+5	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Santiago de Compostela Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase using L-3,4- dihydroxyphenylalanine as substrate measured for 5 mins by spectrophotometric analysis				Bioorg Med Chem Lett 21: 3342-5 (2011) Article DOI: 10.1016/j.bmcl.2011.04.012 BindingDB Entry DOI: 10.7270/Q2QF8T68
					More data for this Ligand-Target Pair