BDBM50344176 (R)-2-(7-(2-(3-chloro-4-fluorophenyl)-N-methylacetamido)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl)acetic acid::CHEMBL1778514

SMILES: CN([C@@H]1CCc2c(CC(O)=O)c3ccccc3n2C1)C(=O)Cc1ccc(F)c(Cl)c1

InChI Key: InChIKey=ASVRWAPQHQZMQU-OAHLLOKOSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344176   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM50344176 ((R)-2-(7-(2-(3-chloro-4-fluorophenyl)-N-methylacet...) Show SMILES CN([C@@H]1CCc2c(CC(O)=O)c3ccccc3n2C1)C(=O)Cc1ccc(F)c(Cl)c1 |r| Show InChI InChI=1S/C23H22ClFN2O3/c1-26(22(28)11-14-6-8-19(25)18(24)10-14)15-7-9-21-17(12-23(29)30)16-4-2-3-5-20(16)27(21)13-15/h2-6,8,10,15H,7,9,11-13H2,1H3,(H,29,30)/t15-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Curated by ChEMBL					Assay Description Binding affinity to human CRTH2 receptor expressed in HEK293-EBNA cells by radioligand competition binding assay				Bioorg Med Chem Lett 21: 3471-4 (2011) Article DOI: 10.1016/j.bmcl.2011.03.085 BindingDB Entry DOI: 10.7270/Q2T72HSR
					More data for this Ligand-Target Pair