BDBM50344368 3-(4-chloro-3-(trifluoromethyl)phenyl)-1-(7-hydroxynaphthalen-1-yl)-1-methylurea::CHEMBL1779832

SMILES: CN(C(=O)Nc1ccc(Cl)c(c1)C(F)(F)F)c1cccc2ccc(O)cc12

InChI Key: InChIKey=HTBNCNCEGXQGKK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344368   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50344368 (3-(4-chloro-3-(trifluoromethyl)phenyl)-1-(7-hydrox...) Show SMILES CN(C(=O)Nc1ccc(Cl)c(c1)C(F)(F)F)c1cccc2ccc(O)cc12 Show InChI InChI=1S/C19H14ClF3N2O2/c1-25(17-4-2-3-11-5-7-13(26)10-14(11)17)18(27)24-12-6-8-16(20)15(9-12)19(21,22)23/h2-10,26H,1H3,(H,24,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Yakuhin, Ltd Curated by ChEMBL					Assay Description Antagonist activity at human TRPV1 expressed in CHO cells co-expressing aequorin and CRE-luciferase reporter gene assessed as inhibition of capsaicin...				Bioorg Med Chem Lett 21: 3354-7 (2011) Article DOI: 10.1016/j.bmcl.2011.04.013 BindingDB Entry DOI: 10.7270/Q2NG4QXN
					More data for this Ligand-Target Pair