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SMILES: Oc1cccc(CNC(=O)Nc2cccc(F)c2)c1

InChI Key: InChIKey=BNDDYOAVOXATGW-UHFFFAOYSA-N

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344375   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Rattus norvegicus (rat))
BDBM50344375
PNG
(1-(3-fluorophenyl)-3-(3-hydroxybenzyl)urea | CHEMB...)
Show SMILES Oc1cccc(CNC(=O)Nc2cccc(F)c2)c1
Show InChI InChI=1S/C14H13FN2O2/c15-11-4-2-5-12(8-11)17-14(19)16-9-10-3-1-6-13(18)7-10/h1-8,18H,9H2,(H2,16,17,19)
PDB
MMDB

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Bayer Yakuhin, Ltd

Curated by ChEMBL


Assay Description
Antagonist activity at rat TRPV1 expressed in CHO cells co-expressing aequorin and CRE-luciferase reporter gene assessed as inhibition of capsaicin-i...


Bioorg Med Chem Lett 21: 3354-7 (2011)


Article DOI: 10.1016/j.bmcl.2011.04.013
BindingDB Entry DOI: 10.7270/Q2NG4QXN
More data for this
Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))
BDBM50344375
PNG
(1-(3-fluorophenyl)-3-(3-hydroxybenzyl)urea | CHEMB...)
Show SMILES Oc1cccc(CNC(=O)Nc2cccc(F)c2)c1
Show InChI InChI=1S/C14H13FN2O2/c15-11-4-2-5-12(8-11)17-14(19)16-9-10-3-1-6-13(18)7-10/h1-8,18H,9H2,(H2,16,17,19)
PDB
MMDB

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KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Bayer Yakuhin, Ltd

Curated by ChEMBL


Assay Description
Antagonist activity at human TRPV1 expressed in CHO cells co-expressing aequorin and CRE-luciferase reporter gene assessed as inhibition of capsaicin...


Bioorg Med Chem Lett 21: 3354-7 (2011)


Article DOI: 10.1016/j.bmcl.2011.04.013
BindingDB Entry DOI: 10.7270/Q2NG4QXN
More data for this
Ligand-Target Pair