BDBM50344667 6,8-dichloro-4-((5-(4-chlorophenyl)-4-(3,3,3-trifluoropropyl)-4H-1,2,4-triazol-3-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one::CHEMBL1779215

SMILES: FC(F)(F)CCn1c(CN2C(=O)COc3c(Cl)cc(Cl)cc23)nnc1-c1ccc(Cl)cc1

InChI Key: InChIKey=ATXOMMBEQIPAPF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344667   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50344667 (6,8-dichloro-4-((5-(4-chlorophenyl)-4-(3,3,3-trifl...) Show SMILES FC(F)(F)CCn1c(CN2C(=O)COc3c(Cl)cc(Cl)cc23)nnc1-c1ccc(Cl)cc1 Show InChI InChI=1S/C20H14Cl3F3N4O2/c21-12-3-1-11(2-4-12)19-28-27-16(29(19)6-5-20(24,25)26)9-30-15-8-13(22)7-14(23)18(15)32-10-17(30)31/h1-4,7-8H,5-6,9-10H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-Glucose uptake using [14C]-methyl glucopyranoside after 60 mins by m...				Bioorg Med Chem Lett 21: 3774-9 (2011) Article DOI: 10.1016/j.bmcl.2011.04.053 BindingDB Entry DOI: 10.7270/Q2KK9C32
					More data for this Ligand-Target Pair