BDBM50344672 CHEMBL1779220::rac-6,8-dichloro-4-((5-(1,2,3,4-tetrahydronaphthalen-2-yl)-4-(3,3,3-trifluoropropyl)-4H-1,2,4-triazol-3-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one

SMILES: FC(F)(F)CCn1c(CN2C(=O)COc3c(Cl)cc(Cl)cc23)nnc1C1CCc2ccccc2C1

InChI Key: InChIKey=BUHKRSAWQPIHBQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344672   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50344672 (CHEMBL1779220 | rac-6,8-dichloro-4-((5-(1,2,3,4-te...) Show SMILES FC(F)(F)CCn1c(CN2C(=O)COc3c(Cl)cc(Cl)cc23)nnc1C1CCc2ccccc2C1 Show InChI InChI=1S/C24H21Cl2F3N4O2/c25-17-10-18(26)22-19(11-17)33(21(34)13-35-22)12-20-30-31-23(32(20)8-7-24(27,28)29)16-6-5-14-3-1-2-4-15(14)9-16/h1-4,10-11,16H,5-9,12-13H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-Glucose uptake using [14C]-methyl glucopyranoside after 60 mins by m...				Bioorg Med Chem Lett 21: 3774-9 (2011) Article DOI: 10.1016/j.bmcl.2011.04.053 BindingDB Entry DOI: 10.7270/Q2KK9C32
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