BDBM50344677 6-chloro-3-oxo-4-((5-(pyridin-2-yl)-4-(3,3,3-trifluoropropyl)-4H-1,2,4-triazol-3-yl)methyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine-8-carbonitrile::CHEMBL1779337

SMILES: FC(F)(F)CCn1c(CN2C(=O)COc3c(cc(Cl)cc23)C#N)nnc1-c1ccccn1

InChI Key: InChIKey=JDNQWCFSKPECIF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344677   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50344677 (6-chloro-3-oxo-4-((5-(pyridin-2-yl)-4-(3,3,3-trifl...) Show SMILES FC(F)(F)CCn1c(CN2C(=O)COc3c(cc(Cl)cc23)C#N)nnc1-c1ccccn1 Show InChI InChI=1S/C20H14ClF3N6O2/c21-13-7-12(9-25)18-15(8-13)30(17(31)11-32-18)10-16-27-28-19(14-3-1-2-5-26-14)29(16)6-4-20(22,23)24/h1-3,5,7-8H,4,6,10-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-Glucose uptake using [14C]-methyl glucopyranoside after 60 mins by m...				Bioorg Med Chem Lett 21: 3774-9 (2011) Article DOI: 10.1016/j.bmcl.2011.04.053 BindingDB Entry DOI: 10.7270/Q2KK9C32
					More data for this Ligand-Target Pair