BDBM50344682 6-chloro-4-((5-(3-methylpyridin-2-yl)-4-propyl-4H-1,2,4-triazol-3-yl)methyl)-8-nitro-2H-benzo[b][1,4]oxazin-3(4H)-one::CHEMBL1779342

SMILES: CCCn1c(CN2C(=O)COc3c2cc(Cl)cc3[N+]([O-])=O)nnc1-c1ncccc1C

InChI Key: InChIKey=UZKJIBCBXAWJTG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344682   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50344682 (6-chloro-4-((5-(3-methylpyridin-2-yl)-4-propyl-4H-...) Show SMILES CCCn1c(CN2C(=O)COc3c2cc(Cl)cc3[N+]([O-])=O)nnc1-c1ncccc1C Show InChI InChI=1S/C20H19ClN6O4/c1-3-7-25-16(23-24-20(25)18-12(2)5-4-6-22-18)10-26-14-8-13(21)9-15(27(29)30)19(14)31-11-17(26)28/h4-6,8-9H,3,7,10-11H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-Glucose uptake using [14C]-methyl glucopyranoside after 60 mins by m...				Bioorg Med Chem Lett 21: 3774-9 (2011) Article DOI: 10.1016/j.bmcl.2011.04.053 BindingDB Entry DOI: 10.7270/Q2KK9C32
					More data for this Ligand-Target Pair