BDBM50344684 (R)-6,8-dimethyl-4-((4-propyl-5-(1,2,3,4-tetrahydronaphthalen-2-yl)-4H-1,2,4-triazol-3-yl)methyl)-2H-benzo[b][1,4]oxazin-3(4H)-one::CHEMBL1779344

SMILES: CCCn1c(CN2C(=O)COc3c(C)cc(C)cc23)nnc1[C@@H]1CCc2ccccc2C1

InChI Key: InChIKey=NLXNRWHEIIZDBZ-OAQYLSRUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344684   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50344684 ((R)-6,8-dimethyl-4-((4-propyl-5-(1,2,3,4-tetrahydr...) Show SMILES CCCn1c(CN2C(=O)COc3c(C)cc(C)cc23)nnc1[C@@H]1CCc2ccccc2C1 |r| Show InChI InChI=1S/C26H30N4O2/c1-4-11-29-23(15-30-22-13-17(2)12-18(3)25(22)32-16-24(30)31)27-28-26(29)21-10-9-19-7-5-6-8-20(19)14-21/h5-8,12-13,21H,4,9-11,14-16H2,1-3H3/t21-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-Glucose uptake using [14C]-methyl glucopyranoside after 60 mins by m...				Bioorg Med Chem Lett 21: 3774-9 (2011) Article DOI: 10.1016/j.bmcl.2011.04.053 BindingDB Entry DOI: 10.7270/Q2KK9C32
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