BDBM50344685 4-((5-(2,3-dihydro-1H-inden-2-yl)-4-propyl-4H-1,2,4-triazol-3-yl)methyl)-6,8-dimethyl-2H-benzo[b][1,4]oxazin-3(4H)-one::CHEMBL1779345

SMILES: CCCn1c(CN2C(=O)COc3c(C)cc(C)cc23)nnc1C1Cc2ccccc2C1

InChI Key: InChIKey=AISQZZOMEDBDQL-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50344685   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50344685 (4-((5-(2,3-dihydro-1H-inden-2-yl)-4-propyl-4H-1,2,...) Show SMILES CCCn1c(CN2C(=O)COc3c(C)cc(C)cc23)nnc1C1Cc2ccccc2C1 Show InChI InChI=1S/C25H28N4O2/c1-4-9-28-22(26-27-25(28)20-12-18-7-5-6-8-19(18)13-20)14-29-21-11-16(2)10-17(3)24(21)31-15-23(29)30/h5-8,10-11,20H,4,9,12-15H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-Glucose uptake using [14C]-methyl glucopyranoside after 60 mins by m...				Bioorg Med Chem Lett 21: 3774-9 (2011) Article DOI: 10.1016/j.bmcl.2011.04.053 BindingDB Entry DOI: 10.7270/Q2KK9C32
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 1 (SGLT1) (Homo sapiens (Human))	BDBM50344685 (4-((5-(2,3-dihydro-1H-inden-2-yl)-4-propyl-4H-1,2,...) Show SMILES CCCn1c(CN2C(=O)COc3c(C)cc(C)cc23)nnc1C1Cc2ccccc2C1 Show InChI InChI=1S/C25H28N4O2/c1-4-9-28-22(26-27-25(28)20-12-18-7-5-6-8-19(18)13-20)14-29-21-11-16(2)10-17(3)24(21)31-15-23(29)30/h5-8,10-11,20H,4,9,12-15H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human SGLT1				Bioorg Med Chem Lett 21: 3774-9 (2011) Article DOI: 10.1016/j.bmcl.2011.04.053 BindingDB Entry DOI: 10.7270/Q2KK9C32
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Rattus norvegicus)	BDBM50344685 (4-((5-(2,3-dihydro-1H-inden-2-yl)-4-propyl-4H-1,2,...) Show SMILES CCCn1c(CN2C(=O)COc3c(C)cc(C)cc23)nnc1C1Cc2ccccc2C1 Show InChI InChI=1S/C25H28N4O2/c1-4-9-28-22(26-27-25(28)20-12-18-7-5-6-8-19(18)13-20)14-29-21-11-16(2)10-17(3)24(21)31-15-23(29)30/h5-8,10-11,20H,4,9,12-15H2,1-3H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of rat SGLT2				Bioorg Med Chem Lett 21: 3774-9 (2011) Article DOI: 10.1016/j.bmcl.2011.04.053 BindingDB Entry DOI: 10.7270/Q2KK9C32
					More data for this Ligand-Target Pair