BDBM50344689 CHEMBL1779206::N-(6-chloro-4-((5-(4-chlorophenethyl)-4-(3,3,3-trifluoropropyl)-4H-1,2,4-triazol-3-yl)methyl)-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-8-yl)acetamide

SMILES: CC(=O)Nc1cc(Cl)cc2N(Cc3nnc(CCc4ccc(Cl)cc4)n3CCC(F)(F)F)C(=O)COc12

InChI Key: InChIKey=JQMOQZDUFOGXGS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344689   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50344689 (CHEMBL1779206 | N-(6-chloro-4-((5-(4-chloropheneth...) Show SMILES CC(=O)Nc1cc(Cl)cc2N(Cc3nnc(CCc4ccc(Cl)cc4)n3CCC(F)(F)F)C(=O)COc12 Show InChI InChI=1S/C24H22Cl2F3N5O3/c1-14(35)30-18-10-17(26)11-19-23(18)37-13-22(36)34(19)12-21-32-31-20(33(21)9-8-24(27,28)29)7-4-15-2-5-16(25)6-3-15/h2-3,5-6,10-11H,4,7-9,12-13H2,1H3,(H,30,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]-Glucose uptake using [14C]-methyl glucopyranoside after 60 mins by m...				Bioorg Med Chem Lett 21: 3774-9 (2011) Article DOI: 10.1016/j.bmcl.2011.04.053 BindingDB Entry DOI: 10.7270/Q2KK9C32
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