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SMILES: N[C@@H](CC(=O)N1CCN(Cn2nnc3ccccc23)C(=O)C1)Cc1cc(F)c(F)cc1F

InChI Key: InChIKey=CUNRIPAQGSEDEQ-CQSZACIVSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344765   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dipeptidyl peptidase 4


(Homo sapiens (Human))		BDBM50344765
PNG
((R)-1-((1H-benzo[d][1,2,3]triazol-1-yl)methyl)-4-(...)
Show SMILES N[C@@H](CC(=O)N1CCN(Cn2nnc3ccccc23)C(=O)C1)Cc1cc(F)c(F)cc1F |r|
Show InChI InChI=1S/C21H21F3N6O2/c22-15-10-17(24)16(23)8-13(15)7-14(25)9-20(31)28-5-6-29(21(32)11-28)12-30-19-4-2-1-3-18(19)26-27-30/h1-4,8,10,14H,5-7,9,11-12,25H2/t14-/m1/s1
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n/an/a 42.7n/an/an/an/an/an/a



Dong-A Pharm. Co., Ltd

Curated by ChEMBL


Assay Description
Inhibition of recombinant human DPP-4 assessed as H-Gly-Pro-AMC cleavage after 1 hr by fluorescence assay

Bioorg Med Chem Lett 21: 3809-12 (2011)


Article DOI: 10.1016/j.bmcl.2011.04.029
BindingDB Entry DOI: 10.7270/Q2XS5VQK
More data for this
Ligand-Target Pair