BDBM50344798 4-(5-(2,5-dichlorophenyl)furan-2-carboxamido)-3,5-dimethylbenzyl acetate::CHEMBL1779733

SMILES: CC(=O)OCc1cc(C)c(NC(=O)c2ccc(o2)-c2cc(Cl)ccc2Cl)c(C)c1

InChI Key: InChIKey=LAMALDFRIXECQV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344798   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingosine 1-phosphate receptor 4 (Homo sapiens (Human))	BDBM50344798 (4-(5-(2,5-dichlorophenyl)furan-2-carboxamido)-3,5-...) Show SMILES CC(=O)OCc1cc(C)c(NC(=O)c2ccc(o2)-c2cc(Cl)ccc2Cl)c(C)c1 Show InChI InChI=1S/C22H19Cl2NO4/c1-12-8-15(11-28-14(3)26)9-13(2)21(12)25-22(27)20-7-6-19(29-20)17-10-16(23)4-5-18(17)24/h4-10H,11H2,1-3H3,(H,25,27)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Antagonist activity at S1P4 receptor in human U2OS cells expressing EDG6-linked GAL4-VP16 transcription factor via TEV protease site/beta-arrestin/TE...				Bioorg Med Chem Lett 21: 3632-6 (2011) Article DOI: 10.1016/j.bmcl.2011.04.097 BindingDB Entry DOI: 10.7270/Q2T1540Z
					More data for this Ligand-Target Pair