BDBM50344809 CHEMBL1779914::N-(2,6-dimethylphenyl)-5-(thiophen-2-yl)furan-2-carboxamide

SMILES: Cc1cccc(C)c1NC(=O)c1ccc(o1)-c1cccs1

InChI Key: InChIKey=AFJMCYKWIVQVNW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344809   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sphingosine 1-phosphate receptor 4 (Homo sapiens (Human))	BDBM50344809 (CHEMBL1779914 | N-(2,6-dimethylphenyl)-5-(thiophen...) Show SMILES Cc1cccc(C)c1NC(=O)c1ccc(o1)-c1cccs1 Show InChI InChI=1S/C17H15NO2S/c1-11-5-3-6-12(2)16(11)18-17(19)14-9-8-13(20-14)15-7-4-10-21-15/h3-10H,1-2H3,(H,18,19)	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	118	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Antagonist activity at S1P4 receptor in human U2OS cells expressing EDG6-linked GAL4-VP16 transcription factor via TEV protease site/beta-arrestin/TE...				Bioorg Med Chem Lett 21: 3632-6 (2011) Article DOI: 10.1016/j.bmcl.2011.04.097 BindingDB Entry DOI: 10.7270/Q2T1540Z
					More data for this Ligand-Target Pair