BDBM50344824 1-(4-chlorobenzyl)-3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-3-hydroxyindolin-2-one::CHEMBL1779925

SMILES: OC1(C(=O)N(Cc2ccc(Cl)cc2)c2ccccc12)c1ccc2OCCOc2c1

InChI Key: InChIKey=IHLYQXYXUNPCPO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344824   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium channel protein type 9 subunit alpha (Homo sapiens (Human))	BDBM50344824 (1-(4-chlorobenzyl)-3-(2,3-dihydrobenzo[b][1,4]diox...) Show SMILES OC1(C(=O)N(Cc2ccc(Cl)cc2)c2ccccc12)c1ccc2OCCOc2c1 Show InChI InChI=1S/C23H18ClNO4/c24-17-8-5-15(6-9-17)14-25-19-4-2-1-3-18(19)23(27,22(25)26)16-7-10-20-21(13-16)29-12-11-28-20/h1-10,13,27H,11-12,14H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Xenon Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assay				Bioorg Med Chem Lett 21: 3676-81 (2011) Article DOI: 10.1016/j.bmcl.2011.04.088 BindingDB Entry DOI: 10.7270/Q2PC32PJ
					More data for this Ligand-Target Pair