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SMILES: CCCCCN1C(=O)C(CC(N)=O)(c2ccccc12)c1ccc2OCOc2c1

InChI Key: InChIKey=NMASKDHVUOOYAM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344864   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Sodium channel protein type 9 subunit alpha


(Homo sapiens (Human))		BDBM50344864
PNG
(2-(3-(benzo[d][1,3]dioxol-5-yl)-2-oxo-1-pentylindo...)
Show SMILES CCCCCN1C(=O)C(CC(N)=O)(c2ccccc12)c1ccc2OCOc2c1
Show InChI InChI=1S/C22H24N2O4/c1-2-3-6-11-24-17-8-5-4-7-16(17)22(21(24)26,13-20(23)25)15-9-10-18-19(12-15)28-14-27-18/h4-5,7-10,12H,2-3,6,11,13-14H2,1H3,(H2,23,25)
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Article
PubMed
n/an/a>5.00E+3n/an/an/an/an/an/a



Xenon Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assay

Bioorg Med Chem Lett 21: 3676-81 (2011)


Article DOI: 10.1016/j.bmcl.2011.04.088
BindingDB Entry DOI: 10.7270/Q2PC32PJ
More data for this
Ligand-Target Pair