BDBM50345050 2-(6-(4-((dimethylamino)methyl)pyridin-2-yl)-2-(3-methoxyphenyl)-4-oxoquinazolin-3(4H)-yl)-N-isopropylacetamide::CHEMBL1778955

SMILES: COc1cccc(c1)-c1nc2ccc(cc2c(=O)n1CC(=O)NC(C)C)-c1cc(CN(C)C)ccn1

InChI Key: InChIKey=XFDUHSFGPFRFKM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50345050   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vasopressin V1b receptor (Homo sapiens (Human))	BDBM50345050 (2-(6-(4-((dimethylamino)methyl)pyridin-2-yl)-2-(3-...) Show SMILES COc1cccc(c1)-c1nc2ccc(cc2c(=O)n1CC(=O)NC(C)C)-c1cc(CN(C)C)ccn1 Show InChI InChI=1S/C28H31N5O3/c1-18(2)30-26(34)17-33-27(21-7-6-8-22(14-21)36-5)31-24-10-9-20(15-23(24)28(33)35)25-13-19(11-12-29-25)16-32(3)4/h6-15,18H,16-17H2,1-5H3,(H,30,34)	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
MSD Curated by ChEMBL					Assay Description Displacement of [3H]AVP from human vasopressin V1b receptor expressed in CHO cells co-expressing VIP-luciferase by scintillation counting-based whole...				Bioorg Med Chem Lett 21: 3813-7 (2011) Article DOI: 10.1016/j.bmcl.2011.04.022 BindingDB Entry DOI: 10.7270/Q2CV4J34
					More data for this Ligand-Target Pair