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SMILES: COc1ccc(cc1)-c1cn(C)c(CSc2nc3ccccc3c3nc(C)nn23)n1

InChI Key: InChIKey=LRXMTZJJWITRMA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50345086   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A


(Homo sapiens (Human))		BDBM50345086
PNG
(5-((4-(4-methoxyphenyl)-1-methyl-1H-imidazol-2-yl)...)
Show SMILES COc1ccc(cc1)-c1cn(C)c(CSc2nc3ccccc3c3nc(C)nn23)n1
Show InChI InChI=1S/C22H20N6OS/c1-14-23-21-17-6-4-5-7-18(17)25-22(28(21)26-14)30-13-20-24-19(12-27(20)2)15-8-10-16(29-3)11-9-15/h4-12H,13H2,1-3H3
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n/an/a 65n/an/an/an/an/an/a



H. Lundbeck A/S

Curated by ChEMBL


Assay Description
Inhibition of PDE10A

Bioorg Med Chem Lett 21: 3738-42 (2011)


Article DOI: 10.1016/j.bmcl.2011.04.067
BindingDB Entry DOI: 10.7270/Q24B31PT
More data for this
Ligand-Target Pair