BDBM50345096 2-methyl-5-(pyridin-4-ylmethylthio)-[1,2,4]triazolo[1,5-c]quinazoline::CHEMBL1779389

SMILES: Cc1nc2c3ccccc3nc(SCc3ccncc3)n2n1

InChI Key: InChIKey=MEUJDWDBWQKIQM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50345096   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50345096 (2-methyl-5-(pyridin-4-ylmethylthio)-[1,2,4]triazol...) Show SMILES Cc1nc2c3ccccc3nc(SCc3ccncc3)n2n1 Show InChI InChI=1S/C16H13N5S/c1-11-18-15-13-4-2-3-5-14(13)19-16(21(15)20-11)22-10-12-6-8-17-9-7-12/h2-9H,10H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Inhibition of PDE10A				Bioorg Med Chem Lett 21: 3738-42 (2011) Article DOI: 10.1016/j.bmcl.2011.04.067 BindingDB Entry DOI: 10.7270/Q24B31PT
					More data for this Ligand-Target Pair