BDBM50345104 2-(2-methyl-8-(trifluoromethyl)-[1,2,4]triazolo[1,5-c]quinazolin-5-ylthio)acetonitrile::CHEMBL1779381

SMILES: Cc1nc2c3ccc(cc3nc(SCC#N)n2n1)C(F)(F)F

InChI Key: InChIKey=UWEANCOKGUNOBA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50345104   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50345104 (2-(2-methyl-8-(trifluoromethyl)-[1,2,4]triazolo[1,...) Show SMILES Cc1nc2c3ccc(cc3nc(SCC#N)n2n1)C(F)(F)F Show InChI InChI=1S/C13H8F3N5S/c1-7-18-11-9-3-2-8(13(14,15)16)6-10(9)19-12(21(11)20-7)22-5-4-17/h2-3,6H,5H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Inhibition of PDE10A				Bioorg Med Chem Lett 21: 3738-42 (2011) Article DOI: 10.1016/j.bmcl.2011.04.067 BindingDB Entry DOI: 10.7270/Q24B31PT
					More data for this Ligand-Target Pair