BDBM50345126 (2-methyl-[1,2,4]triazolo[1,5-c]quinazolin-5-ylsulfanyl)-acetic acid ethyl ester::CHEMBL1779262

SMILES: CCOC(=O)CSc1nc2ccccc2c2nc(C)nn12

InChI Key: InChIKey=WDZXSSHLQJNDDR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50345126   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50345126 ((2-methyl-[1,2,4]triazolo[1,5-c]quinazolin-5-ylsul...) Show SMILES CCOC(=O)CSc1nc2ccccc2c2nc(C)nn12 Show InChI InChI=1S/C14H14N4O2S/c1-3-20-12(19)8-21-14-16-11-7-5-4-6-10(11)13-15-9(2)17-18(13)14/h4-7H,3,8H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Inhibition of PDE10A				Bioorg Med Chem Lett 21: 3738-42 (2011) Article DOI: 10.1016/j.bmcl.2011.04.067 BindingDB Entry DOI: 10.7270/Q24B31PT
					More data for this Ligand-Target Pair